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Design for setting Up Medical Laboratories

Just like every other things that have basics requirements, and set-up, Medical Laboratory has it own designs to suit the jobs needs.

When starting a medical laboratory, some basic consideration must be taken into account in bring out laboratories design.

In this post, i will outline seven basics, compulsory design laboratory needs.

1. The Laboratory surface must be impervious to water and must be easy to clean.

2. Working bench in the laboratory must be resistance to chemical attacks, such as acids, alkalis, solvents, and disinfectant.

3. Laboratory is not a restaurant, as such accessing the laboratory is restricted to only authorized personnel.

4. For Safety of workers, laboratory must have safety cabinet and room where possiblity of exposure to biological hazards agent be build and in control.

5. Any door that give access to room where infected organisms is, must carry Bio-hazard label.

6. Mechanically ventilated laboratory must maintain inward airflow by extracting to the external atmosphere.

7. Autoclave must be available at all times for waste material sterilization.

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What is Hypercalcemia?

Hypercalcemia as the name imply is excess of Calcium in the body system.

That is, there are present of Calcium above the normal or reference range in the blood cells.

High level of Calcium (Hypercalcemia) are often found in the following conditions; hypothyroidism, cancer metastases in bones, alkalosis (diet for peptic ulcer) hypervitaminosis.

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What is Hypocalcemia?

The opposite of Hypercalcemia is Hypocalcemia.

It a condition when the present of Calcium in the blood cells doesn’t reach the Normal or Reference range.

Lower level of Calcium in the blood is called Hypocalcemia.

Often Hypocalcemia are found in the following conditions; hypoparathyroidism, Rickets, chronic glomerulonephritis, acute pancreatitis and malabsorption syndrome.

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What is Cholesterol?

Unsaturated steroid alcohol in our blood cells is called Cholesterol.

70 to 80 percent of cholesterol in the plasma are esterified with long chain saturated and unsaturated fatty acids, why 20 to 30 percent exist as free unesterified cholesterol.

Function of Cholesterol

Metabolic precursor for the biosynthesis of bile acids, and steroids hormones, includes male and female sex steroids (androgen and oestrogens) and adrenal steroid hormones ( aldosterones and corticosterone, are the major function of Cholesterol.

Liver, ovaries, testes and adrenal glands synthesise these hormones using cholesterol as the main precursor.

Cholesterol is a major structural components of cell membranes.

As results of it insurability in water, Cholesterol can also help control flow of water soluble products in and out of cells.

In human, 60 to 70 percent of Cholesterol is transported by low density lipoprotein, (LDL), 20 to 35 percent by High Density Lipoprotein (HDL), and 5 to 12 percent by very low Density Lipoprotein (VLDL).

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Post analytical stage

quality control in medical Laboratory come after conclusion of investigation.

In order to maintain health standard guidelines, quality assurance must be there to.

Quality assurance in the post analytical stage includes:

Reporting and verifying Haematological test results.

Taking appropriate actions when a result has serious clinical implications.

Ensuring test results are interpreted correctly and adequate records are kept.

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What is Phospholipid?

Phospholipids are biochemical compound or substance made up of combination of lipids and phosphate.

The substance are ester of glycerol with two fatty acyl group and phosphotidic acid.

Phospholipids has similar chemical structure with triglycerides.

Phospholipids main groups in plasma are; Sphingomyelin, Lecithin and Cephalins.

Phospholipids are one of the important component of plasma membrane.

It is responsible in carrying hydrophobic and hydrophilic charges on their molecules, as such serve as a channels for good interface between highly charged water molecules and neutral lipids for movements of molecules across the membrane.

25 percent Equivalent of phospholipids are moved by Low density lipoprotein, (LDL) 30 percent are moved by High Density Lipoprotein, (HDL) and about 20 percent and moved by Very low density lipoprotein, (VLDL).